Endocrine Abstracts

Context: Teriparatide may represent a possible treatment for hypoparathyroidism when oral supplementation with calcium and calcitriol fail to maintain adequate serum calcium level (SCL). The switch from teriparitide to oral calcium and calcitriol could be challenging and there is no consensus for clinical management.Case presentation: A 50-year-old man was admitted at our Department for teriparatide discontinuation. Three years before admission, the pati...

Hypercalcemia is a frequent metabolic disorder in metastatic breast cancer (BC). Aim of this study was to evaluate the incidence of hypercalcemia due to PHPT in BC patients. The study group included 271 consecutive BC, mean age±S.D. 57.7±11.96 yrs. 100/271(36.9%) evaluated at different times after mastectomy (A) and 171(63.1%) before surgery (B), with no distant metastases. Age matched control group included 108 healthy women (Co) and 70 women with thy...

Background and Objectives: During pregnancy normal thyroid activity undergoes significant changes, including an increase in the amount of iodine intake and maternal renal iodine excretion. Hence, dietary iodine requirements are higher in pregnant women than in non-pregnant ones. This study aimed to assess the nutritional iodine status in a large group of pregnant women and thyroid function according to different iodine intake and thyroid diseases.Methods...

A high incidence of serum anti thyro-peroxidase antibodies (TPOAb) has been found in breast cancer (BC). Aim of this study was to evaluate the predictive value of TPOAb in BC. The study group included 47 women submitted to mastectomy for high malignancy degree BC (tumor size >5 cm and/or n° lymph-nodes >3), followed for 5 years. No patient had distant metastases. All were evaluated for thyroid disorders after breast surgery and before any anti-tumoral adjuvant the...